💊 Medication Severity Assessment & Classification Analysis
📋 Classification Framework & Rationale
🏷️ HTN Flag Classification
HTN Flag = 1 (HTN-Related): Medications specifically indicated for hypertension treatment. These medications directly target blood pressure reduction through various mechanisms including ACE inhibition, angiotensin receptor blocking, calcium channel blocking, diuresis, or direct vasodilation. HTN-related medications require regular blood pressure monitoring and may need dose adjustments based on therapeutic response.
HTN Flag = 0 (Non-HTN-Related): Medications not primarily indicated for hypertension treatment, including statins for cholesterol management, supplements, and other cardiovascular medications that may have secondary effects on blood pressure but are not prescribed specifically for hypertension control.
⚠️ Severity Flag Classification
Severity 0 (No Special Monitoring): Medications that are generally well-tolerated with minimal monitoring requirements. These medications have established safety profiles and do not require frequent laboratory monitoring or specialized clinical oversight beyond routine follow-up.
Severity 1 (Low Complexity/Standard Monitoring): First-line medications with well-established safety profiles requiring standard monitoring protocols. These medications typically need routine blood pressure checks, basic metabolic panels, and standard clinical follow-up at regular intervals.
Severity 2 (Medium Complexity/Enhanced Monitoring): Medications requiring enhanced monitoring due to potential side effects, drug interactions, or the need for dose titration. These medications may require more frequent laboratory monitoring, cardiac monitoring, or specialized clinical assessments.
Severity 3 (High Complexity/Intensive Monitoring): Complex medications reserved for refractory cases or specialized clinical situations. These medications require intensive monitoring, have significant potential for adverse effects, may have complex drug interactions, or are used in specific clinical scenarios requiring specialized expertise and frequent clinical oversight.
📊 Dataset Overview
HTN-Related Medications: 38 (62.3%)
Non-HTN Medications: 23 (37.7%)
Unique Medication Types: 27
📈 Medication Classification Visualizations
Comprehensive Medication Classification Analysis
📋 Severity Level Breakdown
| Severity Level | Description | Count | Percentage | Clinical Rationale |
|---|---|---|---|---|
| Level 0 | No Monitoring Required | 21 | 34.4% | Minimal monitoring requirements, well-established safety profiles |
| Level 1 | Low Complexity/Standard Monitoring | 9 | 14.8% | Standard monitoring protocols, first-line therapies with routine follow-up |
| Level 2 | Medium Complexity/Enhanced Monitoring | 18 | 29.5% | Enhanced monitoring for side effects, drug interactions, or dose titration |
| Level 3 | High Complexity/Intensive Monitoring | 13 | 21.3% | Intensive monitoring required, reserved for complex/refractory cases |
🚨 High-Risk Medications (Severity Level 3)
High-Risk Medications by Category:
ARB:
- Candesartan - HTN-related
- Valsartan - HTN-related
ARB_Combo:
- Sacubitril-Valsartan - HTN-related
BetaBlocker:
- Carvedilol - HTN-related
- Labetalol - HTN-related
CAA:
- Clonidine - HTN-related
- Methyldopa - HTN-related
DirectVasodilator:
- Hydralazine - HTN-related
- Minoxidil - HTN-related
Diuretic:
- Spironolactone - HTN-related
- Bumetanide - HTN-related
HCN_Channel_Blocker:
- Ivabradine - Non-HTN
Nitrate:
- Isosorbide - Non-HTN
🏥 Medication Type Analysis
BetaBlocker (HTN-Related)
Count: 7 medications | Severity Range: 2-3 | Average Severity: 2.3
Examples: Atenolol, Bisoprolol, Carvedilol
Diuretic (HTN-Related)
Count: 6 medications | Severity Range: 1-3 | Average Severity: 2.0
Examples: Chlorthalidone, Furosemide, Hydrochlorothiazide
ARB (HTN-Related)
Count: 5 medications | Severity Range: 1-3 | Average Severity: 1.8
Examples: Candesartan, Losartan, Olmesartan
Statin (Non-HTN)
Count: 5 medications | Severity Range: 0-0 | Average Severity: 0.0
Examples: Atorvastatin, Lovastatin, Pravastatin
CCB (HTN-Related)
Count: 4 medications | Severity Range: 1-2 | Average Severity: 1.5
Examples: Amlodipine, Diltiazem, Nifedipine
Bile_Acid_Sequestrant (Non-HTN)
Count: 3 medications | Severity Range: 0-0 | Average Severity: 0.0
Examples: Cholestyramine, Colesevelam, Colestipol
ACE (HTN-Related)
Count: 2 medications | Severity Range: 1-1 | Average Severity: 1.0
Examples: Enalapril, Lisinopril
Omega3 (Non-HTN)
Count: 2 medications | Severity Range: 0-0 | Average Severity: 0.0
Examples: Icosapent, Omega-3-Acid
DirectVasodilator (HTN-Related)
Count: 2 medications | Severity Range: 3-3 | Average Severity: 3.0
Examples: Hydralazine, Minoxidil
ACE_Combo (HTN-Related)
Count: 2 medications | Severity Range: 2-2 | Average Severity: 2.0
Examples: Benazepril-Hydrochlorothiazide, Lisinopril-Hydrochlorothiazide
📝 Clinical Implementation Guidelines
🎯 Key Recommendations:
- Risk Stratification: Use severity flags to prioritize patients for clinical monitoring intensity and resource allocation
- Care Coordination: Patients on Severity Level 3 medications require specialized clinical oversight and frequent monitoring protocols
📊 Monitoring Framework:
- Level 0-1: Standard care protocols with routine follow-up
- Level 2: Enhanced monitoring with more frequent assessments
- Level 3: Intensive monitoring with specialized clinical expertise required
Report Generated: Medication Severity Assessment & Classification Analysis
Clinical Decision Support Tool for Medication Risk Stratification